U.S. stock futures lower  in pre-market trading for , December 21.The Nasdaq Futures is trading at 6,277.00  with a loss of -0.76% percent or -48.25 point.The Dow Futures is trading at 22,846.00 with  a loss of -0.66% percent or -151.00 point. The S&P 500 Futures is trading at 2,469.00 with a loss of -0.69% percent or -17.25 point.

In overnight trading in the Eastern Hemisphere, Japan’s Nikkei 225 is trading at 20,166.19   with a loss of -1.11% percent or -226.39 point. Hong Kong’s Hang Seng is trading at 25,683.81  up with +0.24% percent or +60.28 point. China’s Shanghai Composite is trading at 2,514.58  with a loss of -0.86% percent or  -21.69 point. India’s BSE Sensex is trading at 36,074.01 with a loss of  -0.98% percent or -357.66 point at 12:15 PM.The FTSE 100 is trading at 6,677.76 with  a loss of -0.51% percent or -34.17 point. Germany’s DAX is trading at 10,549.43  with a loss of -0.58% percent or -61.67 point. France’s CAC 40 is trading at 4,645.76  with a loss of -1.00% percent or -46.69 point. The Stoxx Europe 600 is trading at 334.05  with a loss of  -0.77% percent or -2.56  point.

Friday’s Factors and Events

The move marked the fourth increase this year by the U.S. central bank and the ninth since it began normalizing rates in December 2015. It came despite President Donald Trump’s tweets against rate hikes. On Monday, he said “it is incredible” that “the Fed is even considering yet another interest rate hike” amid the turmoil outside of the U.S.

On the data front, investors are likely to closely monitor Philly Fed manufacturing figures for December at around 8:30 a.m. ET, with the latest jobless claims data scheduled for publication at the same time.

Meanwhile, a four-week and an eight-week bill is set to be auctioned by the Treasury on Thursday. Announcements on three-month, six-month, two-year, five-year and seven-year notes are also expected

Thursday’s Activity

For the day The Nasdaq Composite is trading at 6,528.41  with a loss of -1.63% percent or -108.42 point.the Dow is trading at 22,859.60  with a loss of  -1.99% percent or -464.06 point. The S&P 500 is trading at 2,467.42  with  a loss of -1.58% percent or -39.54 point.

Other leading market index closes included the small-cap Russell 2000 Index closed at 1,326.00  with a loss of -1.72% percent or -23.23 point; the S&P 600 Small-Cap Index closed at 828.10 with a loss of -1.47% percent or -12.36  point; the S&P 400 Mid-Cap Index closed at 1,644.33  with a loss of -1.28% percent or -21.39 point; the S&P 100 Index closed at 1,096.36 with  a loss of -1.54% percent or -17.19 point; the Russell 3000 Index closed at 1,448.56  with a loss of -1.60% percent or -23.62 point; the Russell 1000 Index closed at 1,448.56  with a loss of  -1.60% percent or -23.62 point;